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Regulation of ABC Drug Efflux Transporters in Human T-Cells Exposed to an HIV Pseudotype

ATP-binding cassette (ABC) drug efflux transporters could contribute to low intracellular concentrations of antiretroviral drugs in HIV-1 cell reservoirs and sanctuary sites. Furthermore, the functional expression of these transporters could be induced in activated T-cells. Therefore, we investigate...

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Detalles Bibliográficos
Autores principales: Whyte-Allman, Sana-Kay, Kaul, Rupert, Bendayan, Reina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371480/
https://www.ncbi.nlm.nih.gov/pubmed/34421607
http://dx.doi.org/10.3389/fphar.2021.711999