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STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies with a poor prognosis, and its treatment remains a great challenge. Dihydrotanshinone I (DHTS) has been reported to exert antitumor effect in many cancers. However, the role of DHTS in ESCC remains unclear....

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Detalles Bibliográficos
Autores principales: Qi, Ming-Ming, He, Peng-Zhan, Zhang, Lan, Dong, Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371523/
https://www.ncbi.nlm.nih.gov/pubmed/34457194
http://dx.doi.org/10.4251/wjgo.v13.i8.893