Cargando…

STAT3-mediated activation of mitochondrial pathway contributes to antitumor effect of dihydrotanshinone I in esophageal squamous cell carcinoma cells

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies with a poor prognosis, and its treatment remains a great challenge. Dihydrotanshinone I (DHTS) has been reported to exert antitumor effect in many cancers. However, the role of DHTS in ESCC remains unclear....

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Ming-Ming, He, Peng-Zhan, Zhang, Lan, Dong, Wei-Guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371523/ https://www.ncbi.nlm.nih.gov/pubmed/34457194 http://dx.doi.org/10.4251/wjgo.v13.i8.893

Ejemplares similares

Berberine displays antitumor activity in esophageal cancer cells in vitro
por: Jiang, Shu-Xian, et al.
Publicado: (2017)

Mitochondrial pathway of the lysine demethylase 5C inhibitor CPI-455 in the Eca-109 esophageal squamous cell carcinoma cell line
por: Xue, Xiao-Jie, et al.
Publicado: (2021)

N-linked glycoproteomic profiling in esophageal squamous cell carcinoma
por: Liu, Qi-Wei, et al.
Publicado: (2022)

Identification of a three-gene prognostic signature for radioresistant esophageal squamous cell carcinoma
por: Wang, Xiao-Yan, et al.
Publicado: (2023)

Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway
por: Hu, Dong-Xin, et al.
Publicado: (2022)

Inhibition of bromodomain-containing protein 4 enhances the migration of esophageal squamous cell carcinoma cells by inducing cell autophagy
por: Yang, Wen-Qian, et al.
Publicado: (2022)

Dihydrotanshinone Inhibits Hepatocellular Carcinoma by Suppressing the JAK2/STAT3 Pathway
por: Hu, Xue, et al.
Publicado: (2021)

miR-382 functions as a tumor suppressor against esophageal squamous cell carcinoma
por: Feng, Jie, et al.
Publicado: (2017)

Effects of dietary zinc deficiency on esophageal squamous cell proliferation and the mechanisms involved
por: Chen, Yao, et al.
Publicado: (2021)

Knockdown of lncRNAXLOC_001659 inhibits proliferation and invasion of esophageal squamous cell carcinoma cells
por: Li, Feng-Zhi, et al.
Publicado: (2019)

Down-regulation of miR-30a-3p/5p promotes esophageal squamous cell carcinoma cell proliferation by activating the Wnt signaling pathway
por: Qi, Bo, et al.
Publicado: (2017)

Predicting malignant transformation of esophageal squamous cell lesions by combined biomarkers in an endoscopic screening program
por: Zhang, Hao, et al.
Publicado: (2016)

Circulating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma
por: Terasawa, Hiroyuki, et al.
Publicado: (2021)

KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling
por: Hao, Wei-Wei, et al.
Publicado: (2022)

Therapeutic Antitumor Efficacy of B Cells Loaded With Tumor-derived Autophagasomes Vaccine (DRibbles)
por: Ren, Hongyan, et al.
Publicado: (2014)

Generation of Antitumor T Cells For Adoptive Cell Therapy With Artificial Antigen Presenting Cells
por: Shrestha, Bishwas, et al.
Publicado: (2020)

Chitinase 3-like 1 secreted by peritumoral macrophages in esophageal squamous cell carcinoma is a favorable prognostic factor for survival
por: Xing, Shan, et al.
Publicado: (2017)

Regulation of HuR structure and function by dihydrotanshinone-I
por: Lal, Preet, et al.
Publicado: (2017)

Dihydrotanshinone I inhibits human glioma cell proliferation via the activation of ferroptosis
por: Tan, Shougang, et al.
Publicado: (2020)

Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats
por: Yu, Liuqian, et al.
Publicado: (2020)

Dihydrotanshinone I Alleviates Crystalline Silica-Induced Pulmonary Inflammation by Regulation of the Th Immune Response and Inhibition of STAT1/STAT3
por: Zhang, Yiting, et al.
Publicado: (2019)

Dihydrotanshinone I inhibits hepatocellular carcinoma cells proliferation through DNA damage and EGFR pathway
por: Wang, Linjun, et al.
Publicado: (2023)

Expression of nucleus accumbens-1 in colon cancer negatively modulates antitumor immunity
por: Shen, Zhao-Hua, et al.
Publicado: (2022)

Adenosine 2A receptor contributes to the facilitation of post-infectious irritable bowel syndrome by γδ T cells via the PKA/CREB/NF-κB signaling pathway
por: Dong, Li-Wei, et al.
Publicado: (2023)

Nicotinic receptors modulate antitumor therapy response in triple negative breast cancer cells
por: Español, Alejandro, et al.
Publicado: (2022)

miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer
por: Wang, Jie, et al.
Publicado: (2017)

Effects of Dihydrotanshinone I on Proliferation and Invasiveness of Paclitaxel-Resistant Anaplastic Thyroid Cancer Cells
por: Allegri, Lorenzo, et al.
Publicado: (2021)

Dihydrotanshinone-Induced NOX5 Activation Inhibits Breast Cancer Stem Cell through the ROS/Stat3 Signaling Pathway
por: Kim, Su-Lim, et al.
Publicado: (2019)

CPEB1, a novel risk gene in recent-onset schizophrenia, contributes to mitochondrial complex I defect caused by a defective provirus ERVWE1
por: Xia, Ya-Ru, et al.
Publicado: (2021)

Esophageal magnetic compression anastomosis in dogs
por: Xu, Xiang-Hua, et al.
Publicado: (2022)

Dihydrotanshinone I inhibits the growth of osteosarcoma through the Wnt/β-catenin signaling pathway
por: Tan, Tao, et al.
Publicado: (2019)

DEK overexpression is predictive of poor prognosis in esophageal squamous cell carcinoma
por: Yi, Huochun, et al.
Publicado: (2019)

Molecular mechanisms of apoptosis in hepatocellular carcinoma cells induced by ethanol extracts of Solanum lyratum Thumb through the mitochondrial pathway
por: Mo, Xiao-Qiang, et al.
Publicado: (2017)

Antitumor Potency of an Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, Lisocabtagene Maraleucel in Combination With Ibrutinib or Acalabrutinib
por: Qin, Jim S., et al.
Publicado: (2020)

Loss of host tissue transglutaminase boosts antitumor T cell immunity by altering STAT1/STAT3 phosphorylation in ovarian cancer
por: Sima, Livia Elena, et al.
Publicado: (2021)

Intratracheal administration of umbilical cord-derived mesenchymal stem cells attenuates hyperoxia-induced multi-organ injury via heme oxygenase-1 and JAK/STAT pathways
por: Dong, Na, et al.
Publicado: (2022)

Mitochondrial pathway mediated by reactive oxygen species involvement in α-hederin-induced apoptosis in hepatocellular carcinoma cells
por: Li, Jiao, et al.
Publicado: (2018)

Enhanced Bioavailability of Dihydrotanshinone I–Bovine Serum Albumin Nanoparticles for Stroke Therapy
por: Ren, Yanru, et al.
Publicado: (2021)

Dihydrotanshinone I Inhibits the Growth of Osteosarcoma Through the Wnt/β-Catenin Signaling Pathway [Retraction]
Publicado: (2023)

Dihydrotanshinone I Inhibits the Proliferation and Growth of Oxaliplatin-Resistant Human HCT116 Colorectal Cancer Cells
por: Wang, Mengge, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6j11iljf1lkcuast8hnd3m2c1l