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Circular Ribonucleic Acid circFTO Promotes Angiogenesis and Impairs Blood–Retinal Barrier Via Targeting the miR-128-3p/Thioredoxin Interacting Protein Axis in Diabetic Retinopathy

Background: Increasing attention has been attracted by the role of circular RNAs (circRNAs) in ocular diseases. Previous study has revealed that circ_0005941 (also known as circFTO, an alpha-ketoglutarate–dependent dioxygenase) was upregulated in the vitreous humor of diabetic retinopathy (DR), whil...

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Detalles Bibliográficos
Autores principales: Guo, Jianjin, Xiao, Feng, Ren, Wei, Zhu, Yikun, Du, Qiujing, Li, Qian, Li, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371555/
https://www.ncbi.nlm.nih.gov/pubmed/34422901
http://dx.doi.org/10.3389/fmolb.2021.685466