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Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study

BACKGROUND: Mitochondrial dysfunction has been suggested to play an important role in all stages of multiple sclerosis (MS). OBJECTIVE: To determine the expression of two mitophagy-related proteins, PTEN-induced kinase 1 (PINK1) and PARKIN, in a cohort of Japanese patients with different neuroinflam...

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Detalles Bibliográficos
Autores principales: Cossu, Davide, Yokoyama, Kazumasa, Sechi, Leonardo Antonio, Hattori, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371632/
https://www.ncbi.nlm.nih.gov/pubmed/34421896
http://dx.doi.org/10.3389/fimmu.2021.681386