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Aging Negatively Impacts DNA Repair and Bivalent Formation in the C. elegans Germ Line
Defects in crossover (CO) formation during meiosis are a leading cause of birth defects, embryonic lethality, and infertility. In a wide range of species, maternal aging increases aneuploidy and decreases oocyte quality. In C. elegans which produce oocytes throughout the first half of adulthood, agi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371636/ https://www.ncbi.nlm.nih.gov/pubmed/34422819 http://dx.doi.org/10.3389/fcell.2021.695333 |