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Dysregulation of Cells Cycle and Apoptosis in Human Induced Pluripotent Stem Cells Chondrocytes Through p53 Pathway by HT-2 Toxin: An in vitro Study

Kashin–Beck disease (KBD) mainly damages growth plate of adolescents and is susceptible to both gene and gene–environmental risk factors. HT-2 toxin, which is a primary metabolite of T-2 toxin, was regarded as one of the environmental risk factors of KBD. We used successfully generated KBD human ind...

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Detalles Bibliográficos
Autores principales: Zhang, Yanan, Liu, Huan, Lin, Xialu, Zhang, Feng’e, Meng, Peilin, Tan, Sijia, Lammi, Mikko J., Guo, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371750/
https://www.ncbi.nlm.nih.gov/pubmed/34421989
http://dx.doi.org/10.3389/fgene.2021.677723