CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes

BACKGROUND: Multiple studies rely on ChIP-seq experiments to assess the effect of gene modulation and drug treatments on protein binding and chromatin structure. However, most methods commonly used for the normalization of ChIP-seq binding intensity signals across conditions, e.g., the normalization...

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Detalles Bibliográficos
Autores principales: Polit, Lélia, Kerdivel, Gwenneg, Gregoricchio, Sebastian, Esposito, Michela, Guillouf, Christel, Boeva, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371782/
https://www.ncbi.nlm.nih.gov/pubmed/34404353
http://dx.doi.org/10.1186/s12859-021-04320-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371782/
https://www.ncbi.nlm.nih.gov/pubmed/34404353
http://dx.doi.org/10.1186/s12859-021-04320-3

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