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CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes
BACKGROUND: Multiple studies rely on ChIP-seq experiments to assess the effect of gene modulation and drug treatments on protein binding and chromatin structure. However, most methods commonly used for the normalization of ChIP-seq binding intensity signals across conditions, e.g., the normalization...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371782/ https://www.ncbi.nlm.nih.gov/pubmed/34404353 http://dx.doi.org/10.1186/s12859-021-04320-3 |