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Remote-controllable bone-targeted delivery of estradiol for the treatment of ovariectomy-induced osteoporosis in rats

BACKGROUND: Osteoporosis (OP) is a systemic skeletal disease marked by bone mass reduction and bone tissue destruction. Hormone replacement therapy is an effective treatment for post-menopausal OP, but estrogen has poor tissue selectivity and severe side effects. RESULTS: In this study, we construct...

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Detalles Bibliográficos
Autores principales: Guo, Yuanyuan, Liu, Yongwei, Shi, Chen, Wu, Tingting, Cui, Yongzhi, Wang, Siyuan, Liu, Ping, Feng, Xiaobo, He, Yu, Fu, Dehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371851/
https://www.ncbi.nlm.nih.gov/pubmed/34407835
http://dx.doi.org/10.1186/s12951-021-00976-4