Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy

BACKGROUND: Human CUB and Sushi multiple domains 1 (CSMD1) is a large membrane-bound tumor suppressor in breast cancer. The current study aimed to elucidate the molecular mechanism underlying the effect of CSMD1 in highly invasive triple negative breast cancer (TNBC). METHODS: We examined the antitu...

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Detalles Bibliográficos
Autores principales: Gialeli, Chrysostomi, Tuysuz, Emre Can, Staaf, Johan, Guleed, Safia, Paciorek, Veronika, Mörgelin, Matthias, Papadakos, Konstantinos S., Blom, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371905/
https://www.ncbi.nlm.nih.gov/pubmed/34404439
http://dx.doi.org/10.1186/s13046-021-02042-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8371905/
https://www.ncbi.nlm.nih.gov/pubmed/34404439
http://dx.doi.org/10.1186/s13046-021-02042-1

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