C3G Regulates STAT3, ERK, Adhesion Signaling, and Is Essential for Differentiation of Embryonic Stem Cells

C3G (RAPGEF1), engaged in multiple signaling pathways, is essential for the early development of the mouse. In this study, we have examined its role in mouse embryonic stem cell self-renewal and differentiation. C3G null cells generated by CRISPR mediated knock-in of a targeting vector exhibited enh...

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Detalles Bibliográficos
Autores principales: Vishnu, Vijay V., Muralikrishna, Bh., Verma, Archana, Nayak, Sanjeev Chavan, Sowpati, Divya Tej, Radha, Vegesna, Shekar, P. Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372029/
https://www.ncbi.nlm.nih.gov/pubmed/33624208
http://dx.doi.org/10.1007/s12015-021-10136-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372029/
https://www.ncbi.nlm.nih.gov/pubmed/33624208
http://dx.doi.org/10.1007/s12015-021-10136-8

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