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Macrocyclization strategies for cyclic peptides and peptidomimetics

Peptides are a growing therapeutic class due to their unique spatial characteristics that can target traditionally “undruggable” protein–protein interactions and surfaces. Despite their advantages, peptides must overcome several key shortcomings to be considered as drug leads, including their high c...

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Detalles Bibliográficos
Autores principales: Bechtler, Clément, Lamers, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372203/
https://www.ncbi.nlm.nih.gov/pubmed/34447937
http://dx.doi.org/10.1039/d1md00083g