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Macrocyclization strategies for cyclic peptides and peptidomimetics
Peptides are a growing therapeutic class due to their unique spatial characteristics that can target traditionally “undruggable” protein–protein interactions and surfaces. Despite their advantages, peptides must overcome several key shortcomings to be considered as drug leads, including their high c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372203/ https://www.ncbi.nlm.nih.gov/pubmed/34447937 http://dx.doi.org/10.1039/d1md00083g |