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Automated affinity selection for rapid discovery of peptide binders

In-solution affinity selection (AS) of large synthetic peptide libraries affords identification of binders to protein targets through access to an expanded chemical space. Standard affinity selection methods, however, can be time-consuming, low-throughput, or provide hits that display low selectivit...

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Detalles Bibliográficos
Autores principales: Zhang, Genwei, Li, Chengxi, Quartararo, Anthony J., Loas, Andrei, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372318/
https://www.ncbi.nlm.nih.gov/pubmed/34447564
http://dx.doi.org/10.1039/d1sc02587b