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Automated affinity selection for rapid discovery of peptide binders
In-solution affinity selection (AS) of large synthetic peptide libraries affords identification of binders to protein targets through access to an expanded chemical space. Standard affinity selection methods, however, can be time-consuming, low-throughput, or provide hits that display low selectivit...
Autores principales: | Zhang, Genwei, Li, Chengxi, Quartararo, Anthony J., Loas, Andrei, Pentelute, Bradley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372318/ https://www.ncbi.nlm.nih.gov/pubmed/34447564 http://dx.doi.org/10.1039/d1sc02587b |
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