Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

OBJECTIVE: To investigate how genetics influence the risk of smoking-related systemic lupus erythematosus (SLE) manifestations. METHODS: Patients with SLE (n(discovery cohort)=776, n(replication cohort)=836) were genotyped using the 200K Immunochip single nucleotide polymorphisms (SNP) Array (Illumi...

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Detalles Bibliográficos
Autores principales: Reid, Sarah, Hagberg, Niklas, Sandling, Johanna K, Alexsson, Andrei, Pucholt, Pascal, Sjöwall, Christopher, Lerang, Karoline, Jönsen, Andreas, Gunnarsson, Iva, Syvänen, Ann-Christine, Troldborg, Anne Margrethe, Voss, Anne, Bengtsson, Anders A, Molberg, Øyvind, Jacobsen, Søren, Svenungsson, Elisabet, Rönnblom, Lars, Leonard, Dag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372395/
https://www.ncbi.nlm.nih.gov/pubmed/33766895
http://dx.doi.org/10.1136/annrheumdis-2020-219727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372395/
https://www.ncbi.nlm.nih.gov/pubmed/33766895
http://dx.doi.org/10.1136/annrheumdis-2020-219727

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