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Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus

OBJECTIVE: To investigate how genetics influence the risk of smoking-related systemic lupus erythematosus (SLE) manifestations. METHODS: Patients with SLE (n(discovery cohort)=776, n(replication cohort)=836) were genotyped using the 200K Immunochip single nucleotide polymorphisms (SNP) Array (Illumi...

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Detalles Bibliográficos
Autores principales:	Reid, Sarah, Hagberg, Niklas, Sandling, Johanna K, Alexsson, Andrei, Pucholt, Pascal, Sjöwall, Christopher, Lerang, Karoline, Jönsen, Andreas, Gunnarsson, Iva, Syvänen, Ann-Christine, Troldborg, Anne Margrethe, Voss, Anne, Bengtsson, Anders A, Molberg, Øyvind, Jacobsen, Søren, Svenungsson, Elisabet, Rönnblom, Lars, Leonard, Dag
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Systemic Lupus Erythematosus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372395/ https://www.ncbi.nlm.nih.gov/pubmed/33766895 http://dx.doi.org/10.1136/annrheumdis-2020-219727

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