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Hypoxia alters the expression of ACE2 and TMPRSS2 SARS-CoV-2 cell entry mediators in hCMEC/D3 brain endothelial cells

The mechanisms by which the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induces neurological complications remain to be elucidated. We aimed to identify possible effects of hypoxia on the expression of SARS-CoV-2 cell entry mediators, angiotensin-converting enzyme 2 (ACE2) receptor...

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Detalles Bibliográficos
Autores principales: Imperio, Guinever E., Lye, Phetcharawan, Mughis, Hafsah, Hamada, Hirotaka, Bloise, Enrrico, Lye, Stephen J., Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372440/
https://www.ncbi.nlm.nih.gov/pubmed/34416267
http://dx.doi.org/10.1016/j.mvr.2021.104232