Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors

SARS-CoV-2 as a positive-sense single-stranded RNA coronavirus caused the global outbreak of COVID-19. The main protease (M(pro)) of the virus as the major enzyme processing viral polyproteins contributed to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Jiahua, Jia, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372460/
https://www.ncbi.nlm.nih.gov/pubmed/34438124
http://dx.doi.org/10.1016/j.ejmech.2021.113789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372460/
https://www.ncbi.nlm.nih.gov/pubmed/34438124
http://dx.doi.org/10.1016/j.ejmech.2021.113789

Ejemplares similares