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Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors
SARS-CoV-2 as a positive-sense single-stranded RNA coronavirus caused the global outbreak of COVID-19. The main protease (M(pro)) of the virus as the major enzyme processing viral polyproteins contributed to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Masson SAS.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372460/ https://www.ncbi.nlm.nih.gov/pubmed/34438124 http://dx.doi.org/10.1016/j.ejmech.2021.113789 |