Therapeutic application of estrogen for COVID-19: Attenuation of SARS-CoV-2 spike protein and IL-6 stimulated, ACE2-dependent NOX2 activation, ROS production and MCP-1 upregulation in endothelial cells

The outbreak of COVID-19 has remained uncontained with urgent need for robust therapeutics. We have previously reported sex difference of COVID-19 for the first time indicating male predisposition. Males are more susceptible than females, and more often to develop into severe cases with higher morta...

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Detalles Bibliográficos
Autores principales: Youn, Ji Youn, Zhang, Yixuan, Wu, Yusi, Cannesson, Maxime, Cai, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372492/
https://www.ncbi.nlm.nih.gov/pubmed/34509916
http://dx.doi.org/10.1016/j.redox.2021.102099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372492/
https://www.ncbi.nlm.nih.gov/pubmed/34509916
http://dx.doi.org/10.1016/j.redox.2021.102099

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