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Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time

Phagocytosis by glial cells is essential to regulate brain function during health and disease. Therapies for Alzheimer's disease (AD) have primarily focused on targeting antibodies to amyloid β (Aβ) or inhibitng enzymes that make it, and while removal of Aβ by phagocytosis is protective early i...

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Detalles Bibliográficos
Autores principales: Prakash, Priya, Jethava, Krupal P., Korte, Nils, Izquierdo, Pablo, Favuzzi, Emilia, Rose, Indigo V. L., Guttenplan, Kevin A., Manchanda, Palak, Dutta, Sayan, Rochet, Jean-Christophe, Fishell, Gord, Liddelow, Shane A., Attwell, David, Chopra, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372545/
https://www.ncbi.nlm.nih.gov/pubmed/34476070
http://dx.doi.org/10.1039/d1sc03486c