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Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Phagocytosis by glial cells is essential to regulate brain function during health and disease. Therapies for Alzheimer's disease (AD) have primarily focused on targeting antibodies to amyloid β (Aβ) or inhibitng enzymes that make it, and while removal of Aβ by phagocytosis is protective early i...
Autores principales: | Prakash, Priya, Jethava, Krupal P., Korte, Nils, Izquierdo, Pablo, Favuzzi, Emilia, Rose, Indigo V. L., Guttenplan, Kevin A., Manchanda, Palak, Dutta, Sayan, Rochet, Jean-Christophe, Fishell, Gord, Liddelow, Shane A., Attwell, David, Chopra, Gaurav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372545/ https://www.ncbi.nlm.nih.gov/pubmed/34476070 http://dx.doi.org/10.1039/d1sc03486c |
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