Lifelong reductions of PKMζ in ventral hippocampus of nonhuman primates exposed to early-life adversity due to unpredictable maternal care

Protein kinase Mζ (PKMζ) maintains long-term potentiation (LTP) and long-term memory through persistent increases in kinase expression. Early-life adversity is a precursor to adult mood and anxiety disorders, in part, through persistent disruption of emotional memory throughout life. Here we subject...

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Detalles Bibliográficos
Autores principales: Fulton, Sasha L., Hsieh, Changchi, Atkin, Tobias, Norris, Ryan, Schoenfeld, Eric, Tsokas, Panayiotis, Fenton, André Antonio, Sacktor, Todd Charlton, Coplan, Jeremy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372566/
https://www.ncbi.nlm.nih.gov/pubmed/34400535
http://dx.doi.org/10.1101/lm.053468.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372566/
https://www.ncbi.nlm.nih.gov/pubmed/34400535
http://dx.doi.org/10.1101/lm.053468.121

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