Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease

CONTEXT: Mechanisms underlying pituitary corticotroph adenoma adrenocorticotropin (ACTH) production are poorly understood, yet circulating ACTH levels closely correlate with adenoma phenotype and clinical outcomes. OBJECTIVE: We characterized the 5′ ends of proopiomelanocortin (POMC) gene transcript...

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Detalles Bibliográficos
Autores principales: Araki, Takako, Tone, Yukiko, Yamamoto, Masaaki, Kameda, Hiraku, Ben-Shlomo, Anat, Yamada, Shozo, Takeshita, Akira, Yamamoto, Masato, Kawakami, Yasuhiko, Tone, Masahide, Melmed, Shlomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372657/
https://www.ncbi.nlm.nih.gov/pubmed/34061962
http://dx.doi.org/10.1210/clinem/dgab387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372657/
https://www.ncbi.nlm.nih.gov/pubmed/34061962
http://dx.doi.org/10.1210/clinem/dgab387

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