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Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation

Ketone bodies are bioactive metabolites that function as energy substrates, signaling molecules, and regulators of histone modifications. β-hydroxybutyrate (β-OHB) is utilized in lysine β-hydroxybutyrylation (Kbhb) of histones, and associates with starvation-responsive genes, effectively coupling ke...

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Detalles Bibliográficos
Autores principales: Koronowski, Kevin B., Greco, Carolina M., Huang, He, Kim, Jin-Kwang, Fribourgh, Jennifer L., Crosby, Priya, Mathur, Lavina, Ren, Xuelian, Partch, Carrie L., Jang, Cholsoon, Qiao, Feng, Zhao, Yingming, Sassone-Corsi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372761/
https://www.ncbi.nlm.nih.gov/pubmed/34348140
http://dx.doi.org/10.1016/j.celrep.2021.109487