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Ketogenesis impact on liver metabolism revealed by proteomics of lysine β-hydroxybutyrylation
Ketone bodies are bioactive metabolites that function as energy substrates, signaling molecules, and regulators of histone modifications. β-hydroxybutyrate (β-OHB) is utilized in lysine β-hydroxybutyrylation (Kbhb) of histones, and associates with starvation-responsive genes, effectively coupling ke...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372761/ https://www.ncbi.nlm.nih.gov/pubmed/34348140 http://dx.doi.org/10.1016/j.celrep.2021.109487 |