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Dose-Response Modeling with Summary Data from Developmental Toxicity Studies
Dose-response analysis of binary developmental data (e.g., implant loss, fetal abnormalities) is best done using individual fetus data (identified to litter) or litter-specific statistics such as number of offspring per litter and proportion abnormal. However, such data are not often available to ri...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372781/ https://www.ncbi.nlm.nih.gov/pubmed/27567129 http://dx.doi.org/10.1111/risa.12667 |