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Dose-Response Modeling with Summary Data from Developmental Toxicity Studies

Dose-response analysis of binary developmental data (e.g., implant loss, fetal abnormalities) is best done using individual fetus data (identified to litter) or litter-specific statistics such as number of offspring per litter and proportion abnormal. However, such data are not often available to ri...

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Detalles Bibliográficos
Autores principales: Fox, John F., Hogan, Karen A., Davis, Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372781/
https://www.ncbi.nlm.nih.gov/pubmed/27567129
http://dx.doi.org/10.1111/risa.12667