AMOTL2 mono-ubiquitination by WWP1 promotes contact inhibition by facilitating LATS activation

Contact inhibition is a key cellular phenomenon that prevents cells from hyper-proliferating upon reaching confluence. Although not fully characterized, a critical driver of this process is the Hippo signaling pathway, whose downstream effector yes-associated protein plays pivotal roles in cell grow...

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Detalles Bibliográficos
Autores principales: Hwang, Daehee, Kim, Miju, Kim, Soyeon, Kwon, Mi Ra, Kang, Ye-Seul, Kim, Dahyun, Kang, Ho-Chul, Lim, Dae-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372784/
https://www.ncbi.nlm.nih.gov/pubmed/34404733
http://dx.doi.org/10.26508/lsa.202000953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372784/
https://www.ncbi.nlm.nih.gov/pubmed/34404733
http://dx.doi.org/10.26508/lsa.202000953

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