Phosphorylation of PUF-A/PUM3 on Y259 modulates PUF-A stability and cell proliferation

Human PUF-A/PUM3 is a RNA and DNA binding protein participating in the nucleolar processing of 7S to 5.8S rRNA. The nucleolar localization of PUF-A redistributes to the nucleoplasm upon the exposure to genotoxic agents in cells. However, little is known regarding the roles of PUF-A in tumor progress...

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Detalles Bibliográficos
Autores principales: Lin, Hung-Wei, Lee, Jin-Yu, Chou, Nai-Lin, Shih, Ting-Wei, Chang, Mau-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372891/
https://www.ncbi.nlm.nih.gov/pubmed/34407138
http://dx.doi.org/10.1371/journal.pone.0256282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372891/
https://www.ncbi.nlm.nih.gov/pubmed/34407138
http://dx.doi.org/10.1371/journal.pone.0256282

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