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Phosphorylation of PUF-A/PUM3 on Y259 modulates PUF-A stability and cell proliferation
Human PUF-A/PUM3 is a RNA and DNA binding protein participating in the nucleolar processing of 7S to 5.8S rRNA. The nucleolar localization of PUF-A redistributes to the nucleoplasm upon the exposure to genotoxic agents in cells. However, little is known regarding the roles of PUF-A in tumor progress...
Autores principales: | Lin, Hung-Wei, Lee, Jin-Yu, Chou, Nai-Lin, Shih, Ting-Wei, Chang, Mau-Sun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8372891/ https://www.ncbi.nlm.nih.gov/pubmed/34407138 http://dx.doi.org/10.1371/journal.pone.0256282 |
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