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Mas Receptor Agonist AVE0991 increases surfactant protein expression under hyperoxic conditions in human lung epithelial cells

BACKGROUND: Hyperoxia in pre-term neonates is a known risk factor of bronchopulmonary dysplasia (BPD). Hyperoxia is known to cause oxidative stress, inflammatory changes that leads to surfactant deactivation, and decreased surfactant expression. The previous research has shown short term exposure to...

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Detalles Bibliográficos
Autores principales: Thiruvenkataramani, Ranga Prasanth, Abdul-Hafez, Amal, Gewolb, Ira, Uhal, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373051/
https://www.ncbi.nlm.nih.gov/pubmed/34414259