Preferential import of queuosine-modified tRNAs into Trypanosoma brucei mitochondrion is critical for organellar protein synthesis

Transfer RNAs (tRNAs) are key players in protein synthesis. To be fully active, tRNAs undergo extensive post-transcriptional modifications, including queuosine (Q), a hypermodified 7-deaza-guanosine present in the anticodon of several tRNAs in bacteria and eukarya. Here, molecular and biochemical ap...

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Detalles Bibliográficos
Autores principales: Kulkarni, Sneha, Rubio, Mary Anne T, Hegedűsová, Eva, Ross, Robert L, Limbach, Patrick A, Alfonzo, Juan D, Paris, Zdeněk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373054/
https://www.ncbi.nlm.nih.gov/pubmed/34244755
http://dx.doi.org/10.1093/nar/gkab567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373054/
https://www.ncbi.nlm.nih.gov/pubmed/34244755
http://dx.doi.org/10.1093/nar/gkab567

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