Cargando…

Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC

Bacterial replication is a fast and accurate process, with the bulk of genome duplication being catalyzed by the α subunit of DNA polymerase III within the bacterial replisome. Structural and biochemical studies have elucidated the overall properties of these polymerases, including how they interact...

Descripción completa

Detalles Bibliográficos
Autores principales: Fagan, Sean P, Mukherjee, Purba, Jaremko, William J, Nelson-Rigg, Rachel, Wilson, Ryan C, Dangerfield, Tyler L, Johnson, Kenneth A, Lahiri, Indrajit, Pata, Janice D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373059/
https://www.ncbi.nlm.nih.gov/pubmed/34302475
http://dx.doi.org/10.1093/nar/gkab613