Cargando…
Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC
Bacterial replication is a fast and accurate process, with the bulk of genome duplication being catalyzed by the α subunit of DNA polymerase III within the bacterial replisome. Structural and biochemical studies have elucidated the overall properties of these polymerases, including how they interact...
Autores principales: | Fagan, Sean P, Mukherjee, Purba, Jaremko, William J, Nelson-Rigg, Rachel, Wilson, Ryan C, Dangerfield, Tyler L, Johnson, Kenneth A, Lahiri, Indrajit, Pata, Janice D |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373059/ https://www.ncbi.nlm.nih.gov/pubmed/34302475 http://dx.doi.org/10.1093/nar/gkab613 |
Ejemplares similares
-
Kinetic Characterization of Exonuclease-Deficient Staphylococcus aureus PolC, a C-family Replicative DNA Polymerase
por: Lahiri, Indrajit, et al.
Publicado: (2013) -
Human polymerase kappa uses a template-slippage deletion mechanism, but can realign the slipped strands to favour base substitution mutations over deletions
por: Mukherjee, Purba, et al.
Publicado: (2013) -
Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity
por: Anderson, Andrew P, et al.
Publicado: (2020) -
Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity
por: Zhong, Xuejun, et al.
Publicado: (2008) -
Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases
por: Baruch-Torres, Noe, et al.
Publicado: (2017)