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RNAi and Ino80 complex control rate limiting translocation step that moves rDNA to eroding telomeres

The discovery of HAATI(rDNA), a telomerase-negative survival mode in which canonical telomeres are replaced with ribosomal DNA (rDNA) repeats that acquire chromosome end-protection capability, raised crucial questions as to how rDNA tracts ‘jump’ to eroding chromosome ends. Here, we show that HAATI(...

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Detalles Bibliográficos
Autores principales: Apte, Manasi S, Masuda, Hirohisa, Wheeler, David Lee, Cooper, Julia Promisel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373062/
https://www.ncbi.nlm.nih.gov/pubmed/34244792
http://dx.doi.org/10.1093/nar/gkab586