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RNAi and Ino80 complex control rate limiting translocation step that moves rDNA to eroding telomeres
The discovery of HAATI(rDNA), a telomerase-negative survival mode in which canonical telomeres are replaced with ribosomal DNA (rDNA) repeats that acquire chromosome end-protection capability, raised crucial questions as to how rDNA tracts ‘jump’ to eroding chromosome ends. Here, we show that HAATI(...
Autores principales: | Apte, Manasi S, Masuda, Hirohisa, Wheeler, David Lee, Cooper, Julia Promisel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373062/ https://www.ncbi.nlm.nih.gov/pubmed/34244792 http://dx.doi.org/10.1093/nar/gkab586 |
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