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The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization

The identification of G-quadruplex (G4) binding proteins and insights into their mechanism of action are important for understanding the regulatory functions of G4 structures. Here, we performed an unbiased affinity-purification assay coupled with mass spectrometry and identified 30 putative G4 bind...

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Detalles Bibliográficos
Autores principales: Yan, Kevin Kok-Phen, Obi, Ikenna, Sabouri, Nasim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373067/
https://www.ncbi.nlm.nih.gov/pubmed/34302476
http://dx.doi.org/10.1093/nar/gkab620