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RBFOX2 alters splicing outcome in distinct binding modes with multiple protein partners

RBFOX2 controls the splicing of a large number of transcripts implicated in cell differentiation and development. Parsing RNA-binding protein datasets, we uncover that RBFOX2 can interact with hnRNPC, hnRNPM and SRSF1 to regulate splicing of a broad range of splicing events using different sequence...

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Detalles Bibliográficos
Autores principales: Zhou, Delong, Couture, Sonia, Scott, Michelle S, Abou Elela, Sherif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373071/
https://www.ncbi.nlm.nih.gov/pubmed/34244793
http://dx.doi.org/10.1093/nar/gkab595