noisyR: enhancing biological signal in sequencing datasets by characterizing random technical noise

High-throughput sequencing enables an unprecedented resolution in transcript quantification, at the cost of magnifying the impact of technical noise. The consistent reduction of random background noise to capture functionally meaningful biological signals is still challenging. Intrinsic sequencing v...

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Detalles Bibliográficos
Autores principales: Moutsopoulos, Ilias, Maischak, Lukas, Lauzikaite, Elze, Vasquez Urbina, Sergio A, Williams, Eleanor C, Drost, Hajk-Georg, Mohorianu, Irina I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373073/
https://www.ncbi.nlm.nih.gov/pubmed/34076236
http://dx.doi.org/10.1093/nar/gkab433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373073/
https://www.ncbi.nlm.nih.gov/pubmed/34076236
http://dx.doi.org/10.1093/nar/gkab433

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