Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF–DDX19B interaction

Newly synthesized mRNA is translated during its export through the nuclear pore complex, when its 5′-cap structure is still bound by the nuclear cap-binding complex (CBC), a heterodimer of cap-binding protein (CBP) 80 and CBP20. Despite its critical role in mRNA surveillance, the mechanism by which...

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Detalles Bibliográficos
Autores principales: Park, Yeonkyoung, Park, Joori, Hwang, Hyun Jung, Kim, Leehyeon, Jeong, Kwon, Song, Hyun Kyu, Rufener, Simone C, Mühlemann, Oliver, Kim, Yoon Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373075/
https://www.ncbi.nlm.nih.gov/pubmed/34232997
http://dx.doi.org/10.1093/nar/gkab579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373075/
https://www.ncbi.nlm.nih.gov/pubmed/34232997
http://dx.doi.org/10.1093/nar/gkab579

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