Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis

Super-enhancers are clusters of enhancers associated with cell lineage. They can be powerful gene-regulators and may be useful in cell-type specific viral-vector development. Here, we have screened for endothelial super-enhancers and identified an enhancer from within a cluster that conferred 5–70-f...

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Detalles Bibliográficos
Autores principales: Mushimiyimana, Isidore, Niskanen, Henri, Beter, Mustafa, Laakkonen, Johanna P, Kaikkonen, Minna U, Ylä-Herttuala, Seppo, Laham-Karam, Nihay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373076/
https://www.ncbi.nlm.nih.gov/pubmed/34320216
http://dx.doi.org/10.1093/nar/gkab633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373076/
https://www.ncbi.nlm.nih.gov/pubmed/34320216
http://dx.doi.org/10.1093/nar/gkab633

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