RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data

Chromatin is a tightly packaged structure of DNA and protein within the nucleus of a cell. The arrangement of different protein complexes along the DNA modulates and is modulated by gene expression. Measuring the binding locations and occupancy levels of different transcription factors (TFs) and nuc...

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Detalles Bibliográficos
Autores principales: Mitra, Sneha, Zhong, Jianling, Tran, Trung Q, MacAlpine, David M, Hartemink, Alexander J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373080/
https://www.ncbi.nlm.nih.gov/pubmed/34255854
http://dx.doi.org/10.1093/nar/gkab553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373080/
https://www.ncbi.nlm.nih.gov/pubmed/34255854
http://dx.doi.org/10.1093/nar/gkab553

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