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RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data
Chromatin is a tightly packaged structure of DNA and protein within the nucleus of a cell. The arrangement of different protein complexes along the DNA modulates and is modulated by gene expression. Measuring the binding locations and occupancy levels of different transcription factors (TFs) and nuc...
Autores principales: | Mitra, Sneha, Zhong, Jianling, Tran, Trung Q, MacAlpine, David M, Hartemink, Alexander J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373080/ https://www.ncbi.nlm.nih.gov/pubmed/34255854 http://dx.doi.org/10.1093/nar/gkab553 |
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