Cargando…

RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system

In the cell, stalled ribosomes are rescued through ribosome-associated protein quality-control (RQC) pathways. After splitting of the stalled ribosome, a C-terminal polyalanine ‘tail’ is added to the unfinished polypeptide attached to the tRNA on the 50S ribosomal subunit. In Bacillus subtilis, poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Takada, Hiraku, Crowe-McAuliffe, Caillan, Polte, Christine, Sidorova, Zhanna Yu, Murina, Victoriia, Atkinson, Gemma C, Konevega, Andrey L, Ignatova, Zoya, Wilson, Daniel N, Hauryliuk, Vasili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373112/
https://www.ncbi.nlm.nih.gov/pubmed/34255840
http://dx.doi.org/10.1093/nar/gkab589