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RqcH and RqcP catalyze processive poly-alanine synthesis in a reconstituted ribosome-associated quality control system
In the cell, stalled ribosomes are rescued through ribosome-associated protein quality-control (RQC) pathways. After splitting of the stalled ribosome, a C-terminal polyalanine ‘tail’ is added to the unfinished polypeptide attached to the tRNA on the 50S ribosomal subunit. In Bacillus subtilis, poly...
Autores principales: | Takada, Hiraku, Crowe-McAuliffe, Caillan, Polte, Christine, Sidorova, Zhanna Yu, Murina, Victoriia, Atkinson, Gemma C, Konevega, Andrey L, Ignatova, Zoya, Wilson, Daniel N, Hauryliuk, Vasili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373112/ https://www.ncbi.nlm.nih.gov/pubmed/34255840 http://dx.doi.org/10.1093/nar/gkab589 |
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