Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity

Novel coronavirus disease 2019 (COVID-19) severity is highly variable, with pediatric patients typically experiencing less severe infection than adults and especially the elderly. The basis for this difference is unclear. We find that mRNA and protein expression of angiotensin-converting enzyme 2 (A...

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Detalles Bibliográficos
Autores principales: Inde, Zintis, Croker, Ben A., Yapp, Clarence, Joshi, Gaurav N., Spetz, Johan, Fraser, Cameron, Qin, Xingping, Xu, Le, Deskin, Brian, Ghelfi, Elisa, Webb, Gabrielle, Carlin, Aaron F., Zhu, Yanfang Peipei, Leibel, Sandra L., Garretson, Aaron F., Clark, Alex E., Duran, Jason M., Pretorius, Victor, Crotty-Alexander, Laura E., Li, Chendi, Lee, Jamie Casey, Sodhi, Chhinder, Hackam, David J., Sun, Xin, Hata, Aaron N., Kobzik, Lester, Miller, Jeffrey, Park, Jin-Ah, Brownfield, Douglas, Jia, Hongpeng, Sarosiek, Kristopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373124/
https://www.ncbi.nlm.nih.gov/pubmed/34407940
http://dx.doi.org/10.1126/sciadv.abf8609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373124/
https://www.ncbi.nlm.nih.gov/pubmed/34407940
http://dx.doi.org/10.1126/sciadv.abf8609

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