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Stabilization and structural changes of 2D DNA origami by enzymatic ligation

The low thermal stability of DNA nanostructures is the major drawback in their practical applications. Most of the DNA nanotubes/tiles and the DNA origami structures melt below 60°C due to the presence of discontinuities in the phosphate backbone (i.e., nicks) of the staple strands. In molecular bio...

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Detalles Bibliográficos
Autores principales: Rajendran, Arivazhagan, Krishnamurthy, Kirankumar, Giridasappa, Amulya, Nakata, Eiji, Morii, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373134/
https://www.ncbi.nlm.nih.gov/pubmed/34289063
http://dx.doi.org/10.1093/nar/gkab611