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Guanidine-II aptamer conformations and ligand binding modes through the lens of molecular simulation

Regulation of gene expression via riboswitches is a widespread mechanism in bacteria. Here, we investigate ligand binding of a member of the guanidine sensing riboswitch family, the guanidine-II riboswitch (Gd-II). It consists of two stem–loops forming a dimer upon ligand binding. Using extensive mo...

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Detalles Bibliográficos
Autores principales:	Steuer, Jakob, Kukharenko, Oleksandra, Riedmiller, Kai, Hartig, Jörg S, Peter, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373139/ https://www.ncbi.nlm.nih.gov/pubmed/34233001 http://dx.doi.org/10.1093/nar/gkab592

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