The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF

The yeast cyclic AMP-dependent protein kinase A (PKA) is a ubiquitous serine–threonine kinase, encompassing three catalytic (Tpk1–3) and one regulatory (Bcy1) subunits. Evidence suggests PKA involvement in DNA damage checkpoint response, but how DNA repair pathways are regulated by PKA subunits rema...

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Detalles Bibliográficos
Autores principales: Jessulat, Matthew, Amin, Shahreen, Hooshyar, Mohsen, Malty, Ramy, Moutaoufik, Mohamed Taha, Zilocchi, Mara, Istace, Zoe, Phanse, Sadhna, Aoki, Hiroyuki, Omidi, Katayoun, Burnside, Daniel, Samanfar, Bahram, Aly, Khaled A, Golshani, Ashkan, Babu, Mohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373142/
https://www.ncbi.nlm.nih.gov/pubmed/34244791
http://dx.doi.org/10.1093/nar/gkab585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373142/
https://www.ncbi.nlm.nih.gov/pubmed/34244791
http://dx.doi.org/10.1093/nar/gkab585

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