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Genetic vulnerabilities upon inhibition of DNA damage response

Because of essential roles of DNA damage response (DDR) in the maintenance of genomic integrity, cellular homeostasis, and tumor suppression, targeting DDR has become a promising therapeutic strategy for cancer treatment. However, the benefits of cancer therapy targeting DDR are limited mainly due t...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Tang, Mengfan, Chen, Zhen, Nie, Litong, Li, Siting, Xiong, Yun, Szymonowicz, Klaudia Anna, Park, Jeong-Min, Zhang, Huimin, Feng, Xu, Huang, Min, Su, Dan, Hart, Traver, Chen, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373146/
https://www.ncbi.nlm.nih.gov/pubmed/34320214
http://dx.doi.org/10.1093/nar/gkab643